Scientific Publications

69. Cheavegatti-Gianotto, A. et all. - Sugarcane (Saccarum X officinarum): A Reference study for the Regulation of Genetically modified Cultivars in Brazil. Tropical Plant Biol. DOI 10.1007/s12042-011-9068-3 2011 (pdf file 980 KB)


68. Pascon, P.C.; Kitajima, J.P et al. - The complete nucleotide sequence and genomic organization of Citrus Leprosis associated Virus, Cytoplasmatic type (CiLV-C)- Virus Genes 32: 289–298 2006 (pdf file 350 KB)


67. Maccheroni, W., Alegria, M.C., Greggio,C.C., Piazza, J.P., Kamla,R.F., Zacharias, P.R.A., Bar-Joseph, M., Kitajima, E.W., Assumpção, L.C., Camarotte, G., Cardozo, J., Casagrande, E.C., Ferrari, F., Franco, S.F., Giachetto, P.F., Girasol, A., Jordão, A., Silva, V.H.A., Souza, L.C.A., Aguilar-Vildoso, C.I., Zanca, A.S., Arruda, P., Kitajima, J.P., Reinach, F.C., Ferro, J.A. and da Silva, A.C.R. - Identification and Genomic Characterization of a New Virus (Tymoviridae Family) Associated with Citrus Sudden Death Disease – J. Virology 79: 3028-3037 2005 (pdf file 431 KB)

66. Oliveira, D.C.S.G., Reinach, F.C. - The calcium induced switch in the troponin complex probed by fluorescent mutants of troponin I - Eur. J. Biochem. 270: 2937-2944 2003 (pdf file 1400 KB)

65. Valencia, F.F.V., Paulucci, A.A., Quaggio, R.B., Da Silva, A.C.R., Farah, C.S., Reinach, F.C. - Parallel measurement of Ca2+ -binding and fluorescence emission upon Ca2+ titration of recombinant skeletal muscle troponin C: Measurement of sequential calcium binding to the regulatory sites. J.Biol.Chem. 278: 11007-11014 2003

64. da Silva, A.C.R., Ferro, J.A, Reinach, F.C. et al. – Comparison of the genomes of two Xanthomonas pathogens with differering host specificities. Nature 417: 459-463 2002 (pdf file 390 KB)

63. Ngai, S.M., Pearlstone, J.R., Farah, C.S., Reinach, F.C., Smillie, L.B. and Hodges, R.S.- Studies on Interactions between Troponin I and Troponin C.  J. Cell Biochem. 83: 33-46 2001

62.Oliveira, D.M., Nakaie, C.R., Sousa A.D., Farah C.S. and Reinach, F.C . - Mapping the Domain of Troponin T responsible for the Activation of Actomyosin ATPase Activity. Identification of Residues Involved in Binding to Actin. J.Biol.Chem. 275: 27513-2751 2000

61. Simpson, A. J. G, Reinach, F.C; Arruda, P. et al. - The genome sequence of the plant pathogen Xylella fastidiosa. Nature 406: 151-159 2000. (pdf file 544 KB)

60. Blumenschein, T.M.A., Reinach, F.C. - Analysis of affinity and specificity in an EF-hand site using double mutants cycles. Biochemistry 39(13): 3603-3610 2000

59. Das, K., Ashby, K.D., Smirnov, A.V., Reinach, F.C., Petrich, J.W., and Farah, C.S. - Fluorescence properties of recombinant tropomyosin containing tryptophan, 5-Hydroxytryptophan and 7-Azatryptophan. Photochem. Photobiol. 70(5):719-730 1999

58. Miyamoto, C.A., Fischman, D.A.F. and Reinach, F.C. - The interface between MyBP-C and myosin: site directed mutagenesis of the CX myosin binding domain of MyBP-C J. Muscle Research and Cell Motility 20(7):703-716 1999.

57. Viviani, V.R., Silva, A.C.R., Perez, G.L.O., Santelli, R.V., Bechara, E.J.H. and Reinach, F.C. - Cloning and characterization of the cDNA for the Brazilian larval click-beetle Pyrearinus termitilluminans luciferase. Photochem. Photobiol. 70(2):254-260 1999

56.Farah, C.S.; Reinach, F.C. - Regulatory properties of recombinant tropomyosins containing 5-hydroxytryptophan: Ca-binding to troponin results in a conformational change outside the troponin binding site. Biochemistry 38:10543-10551 1999

55. Stone, D.B., Timmins, P.A., Schneider, D.K., Krylova, I,. Ramos, C.H.I., Reinach, F.C., and Mendelson, R.A. - The Effect of Regulatory Ca2+ on the in situ Structures of Troponin C and Troponin I: A Neutron Scattering Study. J. Mol. Biol. 281(4):689-704 1998

54. Reinach, F.C. Adapting to change in Latin America. Nature 392: 647-648 1998.

53. Malnic, B., Farah, C.S; Reinach, F.C. Regulatory properties of the NH2- and COOH-terminal domains of Troponin T: ATPase activation and binding to troponin I and troponin C. J. Biol. Chem. 273: 10594-10601 1998.

52. Fischman, D.A. and Reinach, F.C. C- and H-Proteins in Guidebook to the Cytoskeletal and Motor Proteins: (Vale and Kreis, eds.), Oxford University Press, 1998.

51. Alonycheva, T., Mikawa,T., Reinach,F.C. and Fischman,D.A. - Isoform-specific interaction of the myosin-binding proteins (MyBPs) with skeletal and cardiac myosin is a property of the C-terminal immunoglobulin domain. J.Biol.Chem. 272(33): 20866-20872 1997.

50. Van Eyk, J.E., Thomas, L.T., Tripet, B., Wiesner, R.J., Pearlstone, J.R., Farah, C.S., Reinach, F.C.; Hodges, R.S. - Distinct regions of troponin I regulate Ca2+ -dependent activation and Ca2+ sensitivity of the acto-S1-TM ATPase activity of the thin filament. J.Biol.Chem. 272(16): 10529-10537 1997.

49. Reinach,F.C., Farah,C.S., Monteiro,P.B., and Malnic,B. Structural Interactions responsible for the assembly of the troponin complex on the muscle thin filament. Cell Structure and Function 22(1): 219-223 1997.

48. Diffee,G.M., Patel,J.R. Reinach,F.C., Greaser,M.L., and Moss,R.L. Altered Kinetics of Contraction in Skeletal Muscle Fibers Containing a Mutant Myosin Regulatory Light Chain with Reduced Divalent Cation Binding. Biophys J. 71(1):341-350 1996

47. Da Silva, A.C.R., Kendrick-Jones, J., and Reinach, F.C. Determinants of ion specificity on EF-hand sites. Conversion of the Ca2+/Mg2+ site of smooth muscle myosin regulatory light chain into a Ca2+ -specific site. J.Biol.Chem. 270(12):6773-6778, 1995.

46. Diffee, G.M., Greaser, M.L., Reinach, F.C., and Moss, R.L. Effects of a non-divalent cation binding mutant of myosin regulatory light chain on tension generation in skinned skeletal muscle fibers. Biophys.J 68:1443-1452, 1995.

45. Farah, C.S. and Reinach, F.C. The troponin complex and regulation of muscle contraction. FASEB J. 9:755-767, 1995.

44. Reinach, F.C. Nemaline Myopathy Mechanisms. NatureGenet. 10(1):8, 1995.

43. Slupsky, C.M., Kay, C.M., Reinach, F.C., Smillie, L.B., and Sykes, B.D. Calcium induced dimerization of troponin C: Mode of interaction and use of trifluorethanol as a denaturant of quarternary structure. Biochemistry 34(22):7365-7375, 1995.

42. Slupsky, C.M., Reinach, F.C., Smillie, L.B., and Sykes, B.D. Solution secondary structure of calcium-saturated troponin C monomer determined by multi-dimensional heteronuclear NMR spectroscopy. Prot.Sci. 4:1279-1290, 1995.

41. Sorenson, M.M., Da Silva, A.C.R., Gouveia, C.S., Sousa, V.P., Oshima, W., Ferro, J.A., and Reinach, F.C. Concerted action of the high affinity calcium binding sites in skeletal muscle troponin C. J.Biol.Chem. 270(17):9770-9777, 1995.

40. Farah, C.S., Miyamoto, C.A., Ramos, C.H.I., Da Silva, A.C.R., Quaggio, R.B., Fujimori, K., Smillie, L.B., and Reinach, F.C. Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I. J.Biol.Chem. 269:5230-5240, 1994.

39. Malnic, B. and Reinach, F.C. Assembly of functional skeletal muscle troponin complex in E. coli. Eur.J.Biochem. 222(1):49-54, 1994.

38. Monteiro, P.B., Lataro, R.C., Ferro, J.A., and Reinach, F.C. Functional alfa-tropomyosin produced in E.coli. A di-peptide extension can substitute the N-terminal acetyl group. J.Biol.Chem. 269:10461-10466, 1994.

37. Pena, S.D.J., Barreto, G., Vago, A.R., Marco, L., Reinach, F.C., Neto, E.D., and Simpson, A.,J.G. Sequence-specific "gene signatures" can be obtained by PCR with single specific primers at low stringency. Proc.Natl.Acad.Sci.(USA) 91:1946-1949, 1994.

36. Da Silva, A.C.R., De Araujo, A.H.B., Herzberg, O., Moult, J., Sorenson, M., and Reinach, F.C. Troponin-C mutants with increased calcium affinity. Eur.J.Biochem. 213:599-604, 1993.

35. Okagaki, T., Weber, F.E., Fischman, D.A., Vaughan, K.T., Mikawa, T., and Reinach, F.C. The major myosin-binding domain of skeletal muscle MyBP-C (C-protein) resides in the COOH-terminal, immunoglobulin C2 motif. J. Cell Biol. 123(3):619-626, 1993.

34. Quaggio, R.B., Ferro, J.A., Monteiro, P.B., and Reinach, F.C. Cloning and expression of chicken skeletal muscle troponin I in Escherichia coli: The role of rare codons on the expression level. Prot.Sci. 2:1053-1056, 1993.

33. Vaughan, K.T., Weber, F.E., Reid, T., Ward, D.C., Reinach, F.C., and Fischman, D.A. Human myosin binding protein H (MyBP-H): Complete sequence, genomic organization, and chromosomal localization. Genomics 16:34-40, 1993.

32. Weber, F.E., Vaughan, K.T., Reinach, F.C., and Fischman, D.A. Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C)--Differential expression, conserved domain structure and chromosome assignment. Eur.J.Biochem. 216:661-669, 1993.

31. Whittle, M.R., Zatz, M., and Reinach, F.C. The use of chromossome 5q markers for confirming the diagnosis of proximal spinal muscular atrophy. Brazilian J.Med.Biol.Res. 26:1157-1173, 1993.

30. Da Silva, A.C.R., Kendrick-Jones, J., and Reinach, F.C. Hybrid Myosin Light Chains Containing a Calcium Specific Site from Troponin C. Eur.J.Biochem. 204:85-91, 1992.

29. Pearlstone, J.R., Borgford, T., Chandra, M., Oikawa, K., Kay, C.M., Herzberg, O., Moult, J., Herklotz, A., Reinach, F.C., and Smillie, L.B. Construction and characterization of a spectral probe mutant of troponin C: Application to analyses of mutants with increased Ca2+ affinity. Biochemistry 31:6545-6553, 1992.

28. Da Silva, A.C.R. and Reinach, F.C. Calcium binding induces conformational changes in muscle regulatory proteins. TIBS 16:53-57, 1991.

27. Kendrick-Jones, J., Rasera da Silva, A.C., Reinach, F.C., Messer, N., Rowe, T., and McLaughlin, P. Recombinant DNA approaches to study the role of the regulatory light chains (RLC) using scallop myosin as a test system. J.Cell Sci. 98 Suppl. 14:55-58, 1991.

26. Reinach, F. and Da Silva, A.C.R. The calcium-binding proteins. Reply. TIBS. 16:207, 1991.

25. Fujimori, K., Sorenson, M., Herzberg, O., Moult, J., and Reinach, F.C. Probing the Ca++ induced conformational transition of troponin C with site directed mutants. Nature 345:182-184, 1990.

24. Vieira de Arruda, M., Reinach, F.C., Colli, W., and Zingales, B. Sequence of the 24Sà ribosomal RNA gene and characterization of a corresponding pseudogene from Trypanosoma cruzi. Mol.Biochem.Parasitol. 40:35-42, 1990.

23. Clayton, L., Reinach, F.C., Chumbley, G.M., and MacLeod, A.R. Organization of the hTMnm gene implications for the evolution of muscle and non-muscle tropomyosins. J.Mol.Biol. 201:507-515, 1988.

22. Ferro, J.A. and Reinach, F.C. The complete sequence of a chicken muscle cDNA encoding the acidic ribosomal protein P1. Eur.J.Biochem. 177:513-516, 1988.

21. Reinach, F.C. and Karlsson, R. Cloning, expression, and site-directed mutagenesis of chicken skeletal muscle troponin C. J.Biol.Chem. 263:2371-2376, 1988.

20. Smillie, L.B., Golosinska, K., and Reinach, F.C. Sequences of complete cDNAs encoding four variants of chicken skeletal muscle troponin T. J.Biol.Chem. 263:18816-18820, 1988.

19. Gooding, C., Reinach, F.C., and MacLeod, A.R. Complete nucleotide sequence of the fast-twich isoform of chicken skeletal muscle a-tropomyosin. Nucleic Acids Res. 15:8105, 1987.

18. MacLeod, A.R., Talbot, K., Reinach, F.C., Houlker, C., Smillie, L.B., Giometti, C.S., and Anderson, N.L. Molecular characterization of human cytosqueletal tropomyosins. In: Molecular Biology of Muscle Development UCLA Symposia on Molecular and Cellular Biology New Series vol.29, edited by Emerson, C., Fischman, D.A., Nadal-Guinard, B., and Siddiqui, M.A.Q.New York:Alan R. Liss Inc. 1986,p. 445-455.

17. MacLeod, A.R., Houlker, C., Reinach, F.C., and Talbot, K. The mRNA and RNA-copy pseudogenes encoding TM30nm, a human cytosqueletal tropomyosin. Nucleic Acids Research 14:8413-8426, 1986.

16. Reinach, F.C., Nagai, K., and Kendrick-Jones, J. Site directed mutagenesis of the regulatory light chain Ca2+/Mg2+ binding site and its role in hybrid myosins. Nature 322:80-83, 1986.

15. Reinach, F.C. and MacLeod, A.R. Tissue specific expression of the human tropomyosin gene involved in the generation of the trk oncogene. Nature 322:648-650, 1986.

14. MacLeod, A.R., Houlker, C., Reinach, F.C., Smillie, L.B., Talbot, K., and Modi, G. A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. Proc.Natl.Acad.Sci.USA 82:7835-7839, 1985.

13. Reinach, F.C. and Fischman, D.A. Recombinant DNA approach for defining the primary structure of monoclonal antibody epitopes. The analysis of a conformational-specific antibody to myosin light chain two. J.Mol.Biol. 181:411-422, 1985.

12. Shimizu, T., Reinach, F.C., Masaki, T., and Fischman, D.A. Analysis of the metal induced conformational change in myosin with a monoclonal antibody to light chain two. J.Mol.Biol. 188:271-282, 1985.

11. Dennis, J.E., Simizu, T., Reinach, F.C., and Fischman, D.A. Localization of C-protein isoforms in chicken skeletal muscle: Ultrastructural detection using monoclonal antibodies. J.Cell Biol. 98:1514-1522, 1984.

10. Katayama, E., Wakabayashi, T., Reinach, F.C., Masaki, T., and Fischman, D.A. Proximity of the reactive lysil residue to the antigenic site in rabbit skeletal myosin against the monoclonal antibody (MF 18) generated against chicken skeletal myosin. J.Biochem.(Tokyo) 95:721-727, 1984.

9. Obinata, T., Reinach, F.C., Bader, D.M., Masaki, T., Kitani, S., and Fischman, D.A. Immunochemical analysis of C-protein isoform transitions during the development of chicken skeletal muscle. Dev. Biol. 101:116-124, 1984.

8. Masaki, T., Bader, D., Reinach, F.C., Shimizu, T., Obinata, T., Shafiq, S., and Fischman, D.A. Monoclonal antibody analysis of myosin heavy chain and C-protein isoforms during myogenesis. In: Molecular and Cellular Control of Muscle Development, edited by Pearson, M.L., Epstein, H.F., and Garrels, J.I.New York:Cold Spring Harbour Laboratory, 1983,p. 405-417.

7. Reinach, F.C., Masaki, T., and Fischman, D.A. Characterization of the C-protein from the posterior latissimus dorsi muscle of the adult chicken: Heterogeneity within a single sarcomere. J.Cell Biol. 96:297-300, 1983.

6. Reinach, F.C. Mecanismo da Contra‡ao Muscular. In: Fisiopatologia do Sistema Nervoso, edited by Canelas, H.M.Sao Paulo:Editora Sarvier, 1983,p. 1-31.

5. Reinach, F.C., Masaki, T., Shafiq, S., Obinata, T., and Fischman, D.A. Isoforms of C-protein in adult skeletal muscle: detection with monoclonal antibodies. J.Cell Biol. 95:78-84, 1982.

4. Amabis, J.M., Reinach, F.C., and Andrews, N. Spermatogenesis in Trichosia pubescens (Diptera: Sciaridae). J.Cell Sci. 63:199-213, 1979.

3. Toledo, A.M.S. and Reinach, F.C. Histofisiologia do tecido muscular. In: Miopatias, edited by Levy, J.A.Sao Paulo:Editora Atheneu, 1978,p. 1-12.

2. Junqueira, L.C.U., Sales, L.M.M., and Reinach, F.C. The presence of spontaneous and induced microfilaments in the melanophores of three species of teleosts. Arch.Histol.Jap. 40:435-443, 1977.

1. Levy, J.A., Macha, N., Toledo, A.M.S., Reinach, F.C., and George, L.L. A congenital myophaty of unknown origin. Arch.Neuro-Psiquiat. 35:318-324, 1977.